The influence of lipoproteins on whole-blood viscosity at multiple shear rates.

Publication/Presentation Date

6-1-2005

Abstract

Whole-blood viscosity appears to be an independent predictor of stroke, carotid intima-media thickening, and carotid atherosclerosis. The purpose of this study was to examine for relationships between whole-blood viscosity and blood lipids in young healthy subjects over a range of shear rates. Twenty-seven healthy men and women aged 10 to 25 years having a range of low-density lipoprotein (LDL) cholesterol values 88 to 258 mg/dL and body mass index z scores -1.18 to 2.64 SDs were studied. Whole-blood viscosity at shear rates from 1 to 1000 per second was measured using an automated capillary viscometer. Blood lipids were measured using standard techniques. Triglyceride-rich lipoproteins were isolated by ultracentrifugation at density of

Volume

54

Issue

6

First Page

764

Last Page

768

ISSN

0026-0495

Disciplines

Medicine and Health Sciences | Pediatrics

PubMedID

15931611

Department(s)

Department of Pediatrics

Document Type

Article

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