The impact of obstructive sleep apnea in children with sickle cell disease and asthma.

Publication/Presentation Date

11-1-2023

Abstract

INTRODUCTION: Asthma and obstructive sleep apnea (OSA) are chronic diseases that disproportionately affect children with sickle cell disease (SCD). The literature describes the negative impact that both conditions have on children with SCD separately; however, the effect of OSA on asthmatic children with OSA is less specific. We hypothesized that the presence of OSA in children with SCD and asthma is associated with specific hematologic markers, worse clinical outcomes, and greater healthcare utilization.

METHODS: We retrospectively evaluated children with both SCD and asthma who underwent polysomnography (PSG). We assessed their demographic information, PSG data, hematologic indices, and healthcare utilization based on the concurrent presence of OSA.

RESULTS: Fifty-nine percent of the cohort had OSA with a lower oxygen saturation (SpO

DISCUSSION: Overall, children with SCD and asthma might be at increased risk for developing OSA, and screening for sleep-disordered breathing should be incorporated as part of their routine care.

Volume

58

Issue

11

First Page

3188

Last Page

3194

ISSN

1099-0496

Disciplines

Medicine and Health Sciences | Pediatrics

PubMedID

37606223

Department(s)

Department of Pediatrics

Document Type

Article

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