Emergence of Candida parapsilosis as the predominant species causing candidemia in children.

Publication/Presentation Date

5-1-1998

Abstract

An increase in the rate of isolation of Candida parapsilosis, relative to other Candida species, in our children's hospital led us to analyze the clinical and epidemiological variables associated with candidemia. We sought to determine if these variables are different for patients infected with C. parapsilosis. All episodes of candidemia occurring over a 7-year period were analyzed retrospectively. Of 81 episodes in 80 patients, 35 (43%) were in neonates, and 46 (57%) were in nonneonates. C. parapsilosis was isolated in 40 episodes (49%). C. parapsilosis was significantly more likely than non-C. parapsilosis species to be associated with prematurity (P = .001), presence of a central venous catheter (P = .002), and use of total parenteral nutrition (P = .03). C. parapsilosis has emerged as the predominant species in our children's hospital. The mortality rate associated with candidemia in children is lower than previously reported and may be associated with the high rate of isolation of C. parapsilosis.

Volume

26

Issue

5

First Page

1086

Last Page

1088

ISSN

1058-4838

Disciplines

Medicine and Health Sciences | Pediatrics

PubMedID

9597232

Department(s)

Department of Pediatrics, Department of Pediatrics Faculty

Document Type

Article

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