Circadian rhythms in gonadotropin excretion in prepubertal and pubertal children.
Publication/Presentation Date
4-1-1976
Abstract
Timed urinary collections were obtained during sleep and waking hours from 27 prepubertal children ranging in age from 2-12 years and from 13 subjects in various stages of puberty, 12-18 years old. The urine samples were extracted with acetone and introduced into FSH and LH radioimmunoassays. Results of the study indicate a significant nocturnal augmentation of LH secretion in pubertal subjects, confirming existing reports using blood sampling techniques. Increased LH and FSH excretion during sleep was also found in prepubertal children.
Volume
42
Issue
4
First Page
770
Last Page
773
ISSN
0021-972X
Published In/Presented At
Kulin, H. E., Moore, R. G., Jr, & Santner, S. J. (1976). Circadian rhythms in gonadotropin excretion in prepubertal and pubertal children. The Journal of clinical endocrinology and metabolism, 42(4), 770–773. https://doi.org/10.1210/jcem-42-4-770
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
1262449
Department(s)
Department of Pediatrics
Document Type
Article