An evaluation of a noninvasive cardiac output measurement using partial carbon dioxide rebreathing in children.
Publication/Presentation Date
12-1-2004
Abstract
Cardiac output (CO) is an important hemodynamic measure that helps to guide the therapy of critically ill patients. Invasive CO assessment in infants and children is often avoided because of the inherent risks. A noninvasive CO monitor that uses partial rebreathing has been recently developed to determine CO via the Fick principle for carbon dioxide. There have been no clinical studies confirming its accuracy in pediatric patients. This is a prospective observational study of 37 childrenleak, we made multiple CO measurements using thermodilution and compared them with noninvasively determined CO measurements. Paired measurements were analyzed for bias, precision, and correlation via Bland-Altman plot and linear regression. Noninvasive measurements showed a linear correlation with thermodilution CO assessment with an r value of 0.83 (P < 0.03). Bland-Altman analysis yielded a bias of -0.27 L/min and a precision +/-1.49 L/min. Cardiac index measurements demonstrated a decreased r value of 0.67 (P = 0.15) and a bias of -0.18 L . min(-1) . m(-2) and precision of +/-2.13 L . min(-1) . m(-2). Differences between partial rebreathing measurements and thermodilution measurements were largest in children with a body surface area of 0.6 m(2) body surface area and >300 mL tidal volume.
Volume
99
Issue
6
First Page
1642
Last Page
1647
ISSN
0003-2999
Published In/Presented At
Levy, R. J., Chiavacci, R. M., Nicolson, S. C., Rome, J. J., Lin, R. J., Helfaer, M. A., & Nadkarni, V. M. (2004). An evaluation of a noninvasive cardiac output measurement using partial carbon dioxide rebreathing in children. Anesthesia and analgesia, 99(6), 1642–1647. https://doi.org/10.1213/01.ANE.0000136952.85278.99
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
15562047
Department(s)
Department of Pediatrics
Document Type
Article