Utility of magnetic resonance imaging in the evaluation of the child with central diabetes insipidus.
Publication/Presentation Date
5-1-2002
Abstract
Because of the association of central diabetes insipidus (CDI) and occult neoplasia, magnetic resonance imaging (MRI) is an important component of the diagnostic evaluation of a child with CDI. In more than 90% of these children, MRI (T1 weighted-image, without contrast) demonstrates an absence of the normal hyperintensity of the posterior pituitary. In one third of patients, the pituitary stalk is also thickened, suggesting infiltrative disease. Of those with a thickened stalk, the etiology of the CDI remains undetermined in about 60% of patients, whereas histiocytosis and occult germinoma each account for approximately 15-20% of patients. In contrast, germinoma is infrequent (3%) in children with CDI and an MRI showing a normal infundibular stalk, though histiocytosis still accounts for 15-20% of patients. In this paper, a diagnostic approach in children with CDI is proposed.
Volume
15 Suppl 2
First Page
681
Last Page
687
ISSN
0334-018X
Published In/Presented At
Alter, C. A., & Bilaniuk, L. T. (2002). Utility of magnetic resonance imaging in the evaluation of the child with central diabetes insipidus. Journal of pediatric endocrinology & metabolism : JPEM, 15 Suppl 2, 681–687. https://doi.org/10.1515/jpem.2002.15.s2.681
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
12092681
Department(s)
Department of Pediatrics
Document Type
Article