MR imaging of Parkinson disease with spin-echo and gradient-echo sequences.
Publication/Presentation Date
1-1-1989
Abstract
High-field MR with both spin-echo and gradient-echo sequences was performed in 21 patients with (idiopathic, drug-responsive) Parkinson disease. The use of gradient echoes allowed more sensitive detection than did spin echoes of susceptibility changes in the putamina and substantia nigra. No statistically significant difference in putaminal hypointensity on long TR/long TE spin-echo sequences or on T2*-weighted images using gradient-echo sequences was observed between Parkinson patients and controls. There was also no statistically significant difference in the frequency of restoration of the signal intensity of the substantia nigra between the two groups of patients. The width of the pars compacta of the substantia nigra in patients with Parkinson disease was 2.12 + 0.82 mm (mean +/- SD). This value in age- and gender-matched controls was 2.67 +/- 0.5. Comparing these two groups with an unpaired t test resulted in a p value less than or equal to .005. Our MR study with spin-echo and gradient-echo images in Parkinson and control patients was able to substantiate and elaborate on previously described MR features of Parkinson disease.
Volume
152
Issue
1
First Page
159
Last Page
165
ISSN
0361-803X
Published In/Presented At
Braffman, B. H., Grossman, R. I., Goldberg, H. I., Stern, M. B., Hurtig, H. I., Hackney, D. B., Bilaniuk, L. T., & Zimmerman, R. A. (1989). MR imaging of Parkinson disease with spin-echo and gradient-echo sequences. AJR. American journal of roentgenology, 152(1), 159–165. https://doi.org/10.2214/ajr.152.1.159
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
2783271
Department(s)
Department of Pediatrics
Document Type
Article