A method for fast multislice T1 measurement: feasibility studies on phantoms, young children, and children with Canavan's disease.
Publication/Presentation Date
4-1-2000
Abstract
We have developed a multislice protocol for quantitative T1 measurements in which the processing time and the acquisition time are under 2 minutes each for a complete brain study of 15 slices. An echoplanar, inversion-recovery image sequence is designed to collect data suitable for analysis using a linear regression algorithm. The precision is approximately twice the noise to signal ratio of the images. The accuracy of the protocol is better than 1% for T1 in the range 0-2 seconds and deviates slightly for longer T1 values. The protocol is insensitive to B1 field values. If needed, the data can be postprocessed using a slow, nonlinear algorithm to give an accuracy of less than 1% and a precision of approximately the noise to signal ratio throughout a range of T1 values from 0 to 4 seconds.
Volume
11
Issue
4
First Page
360
Last Page
367
ISSN
1053-1807
Published In/Presented At
Haselgrove, J., Moore, J., Wang, Z., Traipe, E., & Bilaniuk, L. (2000). A method for fast multislice T1 measurement: feasibility studies on phantoms, young children, and children with Canavan's disease. Journal of magnetic resonance imaging : JMRI, 11(4), 360–367. https://doi.org/10.1002/(sici)1522-2586(200004)11:4<360::aid-jmri3>3.0.co;2-g
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
10767064
Department(s)
Department of Pediatrics
Document Type
Article