Simultaneous infection with respiratory syncytial virus and other respiratory pathogens.
Publication/Presentation Date
8-1-1988
Abstract
The presentation and subsequent course of respiratory syncytial virus (RSV) bronchiolitis may be atypical and unusually severe when simultaneous infection due to other pathogenic agents is present. During the past two years, nine of the 189 pediatric patients hospitalized with documented RSV infection were found to have the following simultaneous isolates from initial respiratory tract specimens: four adenovirus, four pneumococcus, one cytomegalovirus, and one Pneumocystis carinii. Noted complications attributable to the second pathogen included thrombocytopenia and anemia (cytomegalovirus), hepatitis and disseminated intravascular coagulation (adenovirus), and sepsis and osteomyelitis (pneumococcus). Three of the four patients with RSV and adenovirus died of severe respiratory failure despite mechanical ventilation; two of these patients received ribavirin therapy. Rapid identification of RSV is important but should not be a substitute for more comprehensive viral and bacterial evaluation.
Volume
142
Issue
8
First Page
834
Last Page
836
ISSN
0002-922X
Published In/Presented At
Tristram, D. A., Miller, R. W., McMillan, J. A., & Weiner, L. B. (1988). Simultaneous infection with respiratory syncytial virus and other respiratory pathogens. American journal of diseases of children (1960), 142(8), 834–836. https://doi.org/10.1001/archpedi.1988.02150080040017
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
2839976
Department(s)
Department of Pediatrics
Document Type
Article