Evaluation of Health Disparities in Outcomes of Patients With Juvenile Idiopathic Arthritis.
Publication/Presentation Date
11-15-2025
Abstract
OBJECTIVE: Juvenile idiopathic arthritis (JIA) is complicated by morbidity, with suboptimal rates of prolonged remission, decreased health-related quality of life, and functional limitations. The Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN), a North American learning health network, has a centralized registry of patients with JIA to track quality measures. We assessed for health disparities in our collaborative JIA population by evaluating our performance on disease activity outcomes, overall well-being, and pain by race and ethnicity, age, sex, and JIA subtype.
METHODS: A cross-sectional analysis of patients in the PR-COIN registry was conducted to estimate the association between race and ethnicity groups and outcomes including physician global assessment of disease activity (PGA), patient/parent global assessment of overall well-being (PtGA), active joint count, 10-joint clinical Juvenile Arthritis Disease Activity Score (cJADAS10), arthritis-related pain intensity score, and morning stiffness duration.
RESULTS: Data from 9601 patients were analyzed. Current age was positively and significantly associated with higher scores of pain intensity, PGA, PtGA, and cJADAS10. Non-Hispanic Black patients had statistically higher cJADAS10 scores compared to non-Hispanic White patients, in addition to statistically higher pain intensity scores, and PGA and PtGA scores. Female patients had statistically higher scores compared to male patients for all outcome variables assessed.
CONCLUSION: We found disparities in outcomes of patients with JIA related to race and ethnicity, sex, and age. This information is imperative to drive further improvement efforts and understand possible causes of these differences to close disparity gaps and improve outcomes for all patients with JIA.
ISSN
1499-2752
Published In/Presented At
Harris, J. G., Singleton, J. H., Ting, T. V., Oberle, E. J., Burnham, J. M., Mannion, M. L., Bingham, C. A., Weiss, J. E., Laxer, R. M., Shishov, M., Gottlieb, B. S., Gilbert, M., Pan, N., Batthish, M., Fair, D. C., Ray, L., Hazen, M. M., Morgan, E. M., Vora, S. S., & Pediatric Rheumatology Care and Outcomes Improvement Network (2025). Evaluation of Health Disparities in Outcomes of Patients With Juvenile Idiopathic Arthritis. The Journal of rheumatology, jrheum.2025-0313. Advance online publication. https://doi.org/10.3899/jrheum.2025-0313
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
41241401
Department(s)
Department of Pediatrics
Document Type
Article