Benign transient hyperphosphatasemia of infancy and childhood.
Publication/Presentation Date
12-1-2000
Abstract
Six children, aged 11 to 25 months, were found to have elevated serum alkaline phosphatase (ALP) levels (1,077 to 9,271 U/L) in the absence of disease. Benign transient hyperphosphatasemia (BTH) was diagnosed when the serum ALP levels returned to normal or decreased significantly within 3 months. Several theories have been suggested regarding the pathophysiology of BTH, but the exact cause is still unclear. We report six cases of BTH and review the literature. It is important to recognize this condition and to avoid extensive and unnecessary evaluation.
Volume
93
Issue
12
First Page
1162
Last Page
1164
ISSN
0038-4348
Published In/Presented At
Tolaymat, N., & de Melo, M. C. (2000). Benign transient hyperphosphatasemia of infancy and childhood. Southern medical journal, 93(12), 1162–1164.
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
11142449
Department(s)
Department of Pediatrics
Document Type
Article