Non-African Burkitt lymphoma presenting with oral thrush and an orbital mass in a child.
PURPOSE: To report an unusual case of orbital involvement with non-African Burkitt lymphoma in a child.
METHODS: A 26-month-old boy developed oral thrush and painless right proptosis with eyelid swelling. Magnetic resonance imaging disclosed a diffuse mass involving the inferior, lateral, and superior right orbit and both maxillary sinuses. Incisional biopsy of the orbital mass was performed.
RESULTS: Histopathology disclosed diffuse infiltration of the orbital tissues by a high-grade lymphoid neoplasm that showed positive immunoreactivity for B-cell markers. Immunoglobulin gene rearrangement studies disclosed a characteristic t(8;14) translocation consistent with a small, noncleaved malignant lymphoma of the Burkitt type.
CONCLUSION: Non-African Burkitt lymphoma may manifest with orbital involvement.
Published In/Presented At
Gold, H. K., Torres, F. W., Garabedian, H. D., Werner, W., Jang, I. K., Khan, A., Hagstrom, J. N., Yasuda, T., Leinbach, R. C., & Newell, J. B. (1993). Evidence for a rebound coagulation phenomenon after cessation of a 4-hour infusion of a specific thrombin inhibitor in patients with unstable angina pectoris. Journal of the American College of Cardiology, 21(5), 1039–1047. https://doi.org/10.1016/0735-1097(93)90222-m
Medicine and Health Sciences | Pediatrics
Department of Pediatrics