Non-African Burkitt lymphoma presenting with oral thrush and an orbital mass in a child.
Publication/Presentation Date
12-1-1997
Abstract
PURPOSE: To report an unusual case of orbital involvement with non-African Burkitt lymphoma in a child.
METHODS: A 26-month-old boy developed oral thrush and painless right proptosis with eyelid swelling. Magnetic resonance imaging disclosed a diffuse mass involving the inferior, lateral, and superior right orbit and both maxillary sinuses. Incisional biopsy of the orbital mass was performed.
RESULTS: Histopathology disclosed diffuse infiltration of the orbital tissues by a high-grade lymphoid neoplasm that showed positive immunoreactivity for B-cell markers. Immunoglobulin gene rearrangement studies disclosed a characteristic t(8;14) translocation consistent with a small, noncleaved malignant lymphoma of the Burkitt type.
CONCLUSION: Non-African Burkitt lymphoma may manifest with orbital involvement.
Volume
124
Issue
6
First Page
859
Last Page
861
ISSN
0002-9394
Published In/Presented At
Edelstein, C., Shields, J. A., Shields, C. L., De Potter, P., Eagle, R. C., Jr, Turtel, L., & Hagstrom, N. (1997). Non-African Burkitt lymphoma presenting with oral thrush and an orbital mass in a child. American journal of ophthalmology, 124(6), 859–861. https://doi.org/10.1016/s0002-9394(14)71714-3
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
9402843
Department(s)
Department of Pediatrics
Document Type
Article