The assessment of diminished testicular function in boys of pubertal age.

Publication/Presentation Date

9-1-1986

Abstract

Nine boys with anorchia and 9 individuals with diminished testicular function were followed between ages 10 and 18 with serial determinations of urine gonadotrophins and serum testosterone. Ten hCG stimulation tests were performed in eight of these patients. Adult levels of LH (greater than 500 mIU/h) and low measurements of serum testosterone (less than 54 ng/dl) confirmed the anorchic state. Boys with diminished testicular reserve exhibited urinary gonadotrophin changes similar to peripubertal anorchic patients but testosterone levels increased progressively with age (90-715 ng/dl). FSH attained adult castrate levels (greater than 1700 mIU/h) by age 13 in these boys and served to distinguish them from normal controls. The longitudinal assessment of basal hormone levels can separate anorchia from diminished testicular reserve in boys of pubertal age and testing with hCG is not required for evaluation.

Volume

25

Issue

3

First Page

283

Last Page

292

ISSN

0300-0664

Disciplines

Medicine and Health Sciences | Pediatrics

PubMedID

3098465

Department(s)

Department of Pediatrics

Document Type

Article

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