The assessment of diminished testicular function in boys of pubertal age.
Publication/Presentation Date
9-1-1986
Abstract
Nine boys with anorchia and 9 individuals with diminished testicular function were followed between ages 10 and 18 with serial determinations of urine gonadotrophins and serum testosterone. Ten hCG stimulation tests were performed in eight of these patients. Adult levels of LH (greater than 500 mIU/h) and low measurements of serum testosterone (less than 54 ng/dl) confirmed the anorchic state. Boys with diminished testicular reserve exhibited urinary gonadotrophin changes similar to peripubertal anorchic patients but testosterone levels increased progressively with age (90-715 ng/dl). FSH attained adult castrate levels (greater than 1700 mIU/h) by age 13 in these boys and served to distinguish them from normal controls. The longitudinal assessment of basal hormone levels can separate anorchia from diminished testicular reserve in boys of pubertal age and testing with hCG is not required for evaluation.
Volume
25
Issue
3
First Page
283
Last Page
292
ISSN
0300-0664
Published In/Presented At
Kulin, H. E., & Santner, S. J. (1986). The assessment of diminished testicular function in boys of pubertal age. Clinical endocrinology, 25(3), 283–292. https://doi.org/10.1111/j.1365-2265.1986.tb01693.x
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
3098465
Department(s)
Department of Pediatrics
Document Type
Article