Peripheral Retinal Haemorrhages in a Patient with MOG-Associated Optic Neuritis.
Publication/Presentation Date
1-1-2024
Abstract
A 15-year-old female presented with headaches and bilateral vision loss. Fundoscopic examination revealed bilateral optic nerve oedema as well as peripheral retinal haemorrhages. Magnetic resonance imaging of the brain showed findings consistent with bilateral optic neuritis. The patient was started on high dose intravenous corticosteroids but her vision failed to improve. The presence of retinal haemorrhages raised concern that a vasculitis was underlying her symptoms, prompting an extensive work-up, which was unrevealing. Plasmapheresis was initiated and the patient's vision eventually improved to 20/20 in both eyes. Ultimately, she was found to be positive for myelin oligodendrocyte glycoprotein (MOG) antibodies, consistent with a diagnosis of MOG-associated optic neuritis. The patient's course was typical for MOG-associated optic neuritis but her peripheral retinal haemorrhages were atypical, which created diagnostic uncertainty. It is important to be aware of the possibility of retinal findings in this disease. We also review potential causes for retinal haemorrhages in optic neuritis.
Volume
48
Issue
3
First Page
176
Last Page
182
ISSN
0165-8107
Published In/Presented At
Wilke, G. A., Spencer, M., Gilman, C. A., Guerriero, R., Bohm, P., Van Stavern, G. P., & Lee, A. R. (2024). Peripheral Retinal Haemorrhages in a Patient with MOG-Associated Optic Neuritis. Neuro-ophthalmology (Aeolus Press), 48(3), 176–182. https://doi.org/10.1080/01658107.2023.2290540
Disciplines
Medicine and Health Sciences | Pediatrics
PubMedID
38756341
Department(s)
Department of Pediatrics
Document Type
Article