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Case report: response to the ERK1/2 inhibitor ulixertinib in BRAF D594G cutaneous melanoma., Zachary Wolfe MD; Julie C Friedland; Sarah Ginn; Aaron U. Blackham MD; Lauren Demberger PA-C; Morgan M. Horton BSN, RN, CCRC; Alyson McIntosh MD; Hina A. Sheikh MD; Jessica Box; Deborah Knoerzer; Bryan Federowicz; Timothy J Stuhlmiller; Mark Shapiro; and Suresh G. Nair MD

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Are pediatric surgery clinics LGBTQ+ inclusive?, William G Wong, Pierce Curran, Paige Koetter, Travis Hoover MD, Rosemary Claire Roden, and Kathryn Martin

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Outcomes of CD19-Targeted Chimeric Antigen Receptor T Cell Therapy for Patients with Reduced Renal Function Including Dialysis., Anthony C Wood, Ariel Perez Perez, Brian Arciola, Kedar N Patel, Grace Johnson, Elizabeth DiMaggio, Christina A Bachmeier, Kayla Reid, Salvatore Carallo, Melanie H Vargas, Rawan Faramand, Julio C Chavez, Bijal Shah, Sameh Gaballa, Farhad Khimani, Hany Elmariah, Taiga Nishihori, Aleksandr Lazaryan, Ciara Freeman, Marco L Davila, Frederick L Locke, Rahul Mhaskar, Claude Bassil, and Michael D Jain

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Editorial Comment: Evidence Supporting Contrast-Enhanced Mammography (CEM) for Monitoring Neoadjuvant Chemotherapy Response and Showing the Potential of Delayed CEM., Stefanie Woodard

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Contrast-Enhanced Mammography: Reviewing the Past and Looking to the Future., Stefanie Woodard and Adrian Murray

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Breast papillomas in the United States: single institution data on underrepresented minorities with a multi-institutional update on incidence., Stefanie Woodard, Kathryn Zamora, Elizabeth Allen, Angela I Choe, Tiffany L Chan, Yufeng Li, Gauri R Khorjekar, Nikki Tirada MD, Stamatia Destounis, Mandy C Weidenhaft, Richard Hartsough, and Jeong Mi Park

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TCF1 and Tox define different subsets of CD4 T cells in patients with Sézary syndrome., Maria Wysocka, Neha Jariwala, Kevin Zhang, Bernice Benoit, and Alain H Rook

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Continuous positive airway pressure care for pediatric obstructive sleep apnea: A long-term quality improvement initiative., Melissa S Xanthopoulos, Ariel A Williamson, Caroline C Burlingame, Olufunke O. Afolabi-Brown MD, Ignacio E Tapia, Christopher Cielo, Melisa Moore, and Suzanne E Beck

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Isotretinoin Laboratory Monitoring in Acne Treatment: A Delphi Consensus Study., Eric Xia, Jane Han, Adam Faletsky, Hilary Baldwin, Katie Beleznay, Vincenzo Bettoli, Brigitte Dréno, Chee Leok Goh, Linda Stein Gold, Harald Gollnick, Maria Isabel Herane, Sewon Kang, Leon Kircik, Julianne Mann, Alexander Nast, Hazel H Oon, Jo Ann See, Megha Tollefson, Guy Webster, Catherine Zip, Jerry Tan, Elliot B Tapper, Diane Thiboutot, Andrea Zaenglein, John Barbieri, and Arash Mostaghimi

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Lovastatin Inhibits RhoA to Suppress Canonical Wnt/β-Catenin Signaling and Alternative Wnt-YAP/TAZ Signaling in Colon Cancer., Yi Xiao, Qin Liu, Nanyin Peng, Yuzhang Li, Danyang Qiu, Tianlun Yang, Richard Kang, Ahsan Usmani, Efosa Amadasu, Cesario V Borlongan, and Guolong Yu

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Cerebral venous thrombosis in a patient with adenomyosis: A case report., Jayant Kumar Yadav, Aakar Thapa, Anjan Bhattarai, Ashmita Kc, Samip Jung Budhathoki, Avinash Chandra, and Reema Rajbhandari

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Racial and Ethnic Disparities in Prostate Cancer Outcomes in the Veterans Affairs Health Care System., Kosj Yamoah, Kyung Min Lee, Shivanshu Awasthi, Patrick R Alba, Cristina Perez, Tori R Anglin-Foote, Brian Robison, Anthony Gao, Scott L DuVall, Evangelia Katsoulakis, Yu-Ning Wong, Sarah C Markt, Brent S Rose, Ryan Burri, Carrie Wang, Okoduwa Aboiralor, Angelina K Fink, Nicholas G Nickols, Julie A Lynch, and Isla P Garraway

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Early outcomes of the Y-incision technique to enlarge the aortic annulus 3 to 4 valve sizes., Bo Yang, Corina Ghita, Alexander Makkinejad, China Green, and Xiaoting Wu

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Stentless Versus Stented Aortic Valve Replacement for Aortic Stenosis., Bo Yang, Alexander Makkinejad, Shinichi Fukuhara, Jeffrey Clemence, Linda Farhat, Aroosa Malik, Xiaoting Wu, Karen Kim, Himanshu Patel, and G Michael Deeb

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Grade 1 Internal Carotid Artery Blunt Cerebrovascular Injury Persistence Risks Stroke With Current Management: An EAST Multicenter Study., Sarah Yang, Emily Esposito, Chance Spalding, Joshua Simpson, Julie A Dunn, Linda Zier, Sigrid Burruss, Paul Kim, Lewis E Jacobson, Jamie Williams, Jeffry Nahmias, Areg Grigorian, Laura Harmon, Anna Gergen, Matthew Chatoor, Rishi Rattan, Andrew J Young, Jose L Pascual, Jason Murry, Adrian W Ong, Alison Muller, Rovinder S. Sandhu MD, Rachel Appelbaum BS, Nikolay Bugaev, Antony Tatar, Khaled Zreik, Mark J Lieser, Thomas M Scalea, Deborah M Stein, and Margaret Lauerman

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Applications of Artificial Intelligence to Office Laryngoscopy: A Scoping Review., Peter Yao, Moon Usman, Yu H Chen, Alexander German MD, Katerina Andreadis, Keith Mages, and Anaïs Rameau

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Automatic classification of informative laryngoscopic images using deep learning., Peter Yao, Dan Witte, Hortense Gimonet, Alexander German MD, Katerina Andreadis, Michael Cheng, Lucian Sulica, Olivier Elemento, Josue Barnes, and Anaïs Rameau

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Causes and Predictors of Heart Failure Hospitalizations Following Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-Analysis., Farah Yasmin, Muhammad Aamir MD, Abdul Moeed, Kinza Iqbal, Aymen Iqbal, Muhammad Sohaib Asghar, Waqas Ullah, Indranee Rajapreyar, and Yevgeniy Brailovsky

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Mitral Valve Replacement: A Review of Current Practices and Considerations in Low and High-Risk Patients., Farah Yasmin, Hala Najeeb, Hasan Fareed Siddiqui, Muhammad Hamayl Zeeshan, Asad Mehdi, Muhammad Sohaib Asghar, Asim Shaikh, and Muhammad Aamir MD

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Efficacy and Safety of Concomitant Tricuspid Repair in Patients Undergoing Mitral Valve Surgery: a Systematic Review and Meta-Analysis., Farah Yasmin, Hala Najeeb, Unaiza Naeem, Abdul Moeed, Farwa Zaidi, Muhammad Sohaib Asghar, and Muhammad Aamir MD

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Early Transcatheter or Surgical Aortic Valve Replacement Versus Conservative Management in Asymptomatic Patients with Severe Aortic Stenosis: A Systematic Review and Meta-Analysis., Farah Yasmin, Asim Shaikh, Muhammad Sohaib Asghar, Hala Najeeb, Abdul Moeed, Eisha Waqar, Muskaan Doulat Ram, Avinash Nankani, Rohan Kumar Ochani, Rumael Jawed, Muhammad Aamir MD, Waqas Ullah, Fahad Waqar, and Drew M Johnson

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A customized early warning score enhanced emergency department patient flow process and clinical outcomes in a COVID-19 pandemic., Ali Yazdanyar; Megan R. Greenberg BS; Zhe Chen; Shuisen Li DO; Marna R. Greenberg DO, MPH, FACEP; Anthony Buonanno MD, MBA; David B. Burmeister DO, FACEP, CPE; and Shadi Jarjous MD

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Inpatient palliative care encounter and 30-day readmission among hospitalizations for heart failure., Ali Yazdanyar, Desire G. Guthier DO, Theresa Maitz DO, Satinder Singh, Dominic Parfianowicz DO, Shuisen Li DO, and Shadi Jarjous MD

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Association between inpatient palliative care encounter and 30-day all-cause readmissions after index hospitalization for chronic obstructive pulmonary disease., Ali Yazdanyar DO, Ashley Vojtek DO, Sachin Gupta, Aditya Iyer, Alaynna C. Kears DO, Kaitlyn Musco MD, Shuisen Li DO, and Shadi Jarjous MD

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A Novel Treatment of Postpartum Depression and Review of Literature., Jennifer Yoon, Jason Gu MD, and Katherine B. Martin MD

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Cecal pneumatosis intestinalis in necrotic colorectal carcinoma, Su-Yuan Yu BS; Christopher Connell DO; Joseph J. Stirparo MD, MBA; and Victor Longo III, DO, MSPAS

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Testicular Adrenal Rest Tumors in a Patient With Congenital Adrenal Hyperplasia, Su-Yuan Yu BS and Kelly Freed MD

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Executive summary: Consensus recommendations for the use of retinoids in ichthyosis and other disorders of cornification in children and adolescents., A Zaenglein

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Congenital Diaphragmatic Hernia With Kidney and Spleen Herniation in the United Arab Emirates: A Case Report., Anas Zahid, Faisal A Nawaz, Ruthwik Duvuru, Yousef S Alabrach, and Aftab Ahmed

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A Review of the Impella Devices., Rami Zein, Chirdeep Patel MD, Adrian Mercado-Alamo, Theodore Schreiber, and Amir Kaki

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Vitamin A-Induced Hypercalcemia in Burn Patients: A Case Study., Ferris Zeitouni, Christina Zhu, Alan Pang, Scott O'Banion, Deepak Bharadia, and John Griswold

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Allogeneic Hematopoietic Cell Transplants as Dynamical Systems: Effect of Early-Term Immune Suppression Intensity on Long-Term T Cell Recovery, Viktoriya Zelikson, Roy Sabo, Myrna Serrano, Younus Aqeel, Savannah Ward, Taha Al Juhaishi, May Aziz, Elizabeth Krieger, Gary Simmons, Catherine Roberts, Jason Reed, Gregory Buck, and Amir Toor MD

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Dynamical Systems Modeling of Early-Term Immune Reconstitution with Different Antithymocyte Globulin Administration Schedules in Allogeneic Stem Cell Transplantation., Viktoriya Zelikson, Gary Simmons, Natasha Raman, Elizabeth Krieger, Anatevka Rebiero, Kelly Hawks, May Aziz, Catherine Roberts, Alden Chesney, Jason Reed, Ronald Gress, and Amir Toor MD

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Office-based Plastic Surgery-Evidence-based Clinical and Administrative Guidelines., Kevin K Zhang, Nihaal Reddy, and Jeffrey E Janis

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Empathy., Wuyang Zhang and Geoffrey G. Hallock MD

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Identifying Patients With Hypoglycemia Using Natural Language Processing: Systematic Literature Review., Yaguang Zheng, Victoria Vaughan Dickson, Saul Blecker, Jason M Ng, Brynne Campbell Rice, Gail D'Eramo Melkus, Liat Shenkar RN, Marie Claire R Mortejo, and Stephen B Johnson

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Dexmedetomidine Reduces Incidences of Ventricular Arrhythmias in Adult Patients: A Meta-Analysis., Qiaonan Zhong, Ashish Kumar, Abhishek Deshmukh, and Courtney E Bennett DO

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Anti-CD80/86 antibodies inhibit inflammatory reaction and improve graft survival in a high-risk murine corneal transplantation rejection model., Jun Zhu, Takenori Inomata, Masahiro Nakamura, Keiichi Fujimoto, Yasutsugu Akasaki, Kenta Fujio, Ai Yanagawa, Koichiro Uchida, Jaemyoung Sung, Naoko Negishi, Ken Nagino, Yuichi Okumura, Maria Miura, Hurramhon Shokirova, Mizu Kuwahara, Kunihiko Hirosawa, Akie Midorikawa-Inomata, Atsuko Eguchi, Tianxiang Huang, Hideo Yagita, Sonoko Habu, Ko Okumura, and Akira Murakami

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Medical photography using mobile devices., Timothy Zoltie, Sigrid A. Blome-Eberwein MD, Sarah Forbes, Mike Theaker, and Walayat Hussain

Books

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Child Maltreatment Assessment, Vol. 1: Physical Signs of Abuse, Debra Esernio-Jenssen MD; Ruchita Doshi DO; and Randell Alexander MD, PhD

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Child Maltreatment Assessment, Volume Three: Investigation, Care, and Prevention, Debra Esernio-Jenssen MD; Ruchita Doshi DO; and Randell Alexander MD, PhD

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Child Treatment Assessment, Volume Two: Sexual, Emotional, and Psychological Abuse, Debra Esernio-Jenssen MD; Ruchita Doshi DO; and Randell Alexander MD, PhD

Book Chapters

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Remdesivir, Abdul Aleem MD and Jiten Kothadia

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Coronavirus (COVID-19) Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT), Abdul Aleem MD and Ahmed Jamal Nadeem

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Coronavirus (COVID-19) Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT), Abdul Aleem MD and Ahmed Jamal Nadeem

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Evaluating And Referring Patients For Outpatient Monoclonal Antibody Therapy For Coronavirus (COVID-19) In The Emergency Department, Abdul Aleem MD, Olubunmi Olarewaju, and Alexander Pozun

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Emerging Variants of SARS-CoV-2 And Novel Therapeutics Against Coronavirus (COVID-19), Abdul Aleem MD, Abdul Bari Akbar Samad, and Amy Slenker MD

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Fascial Dehiscence, Abdul Aleem MD and Rovinder S. Sandhu MD

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Annular Pancreas, Abdul Aleem MD and Hiral N. Shah MD

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Atezolizumab, Abdul Aleem MD and Hiral N. Shah MD

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Gastric Varices, Abdul Aleem MD and Hiral N. Shah MD

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Gastrointestinal And Hepatic Manifestations Of Coronavirus (COVID-19), Abdul Aleem MD and Hiral N. Shah MD

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Monoclonal Antibody Therapy For High-Risk Coronavirus (COVID 19) Patients With Mild To Moderate Disease Presentations, Abdul Aleem MD and Amy Slenker MD

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Poisoning, Alexandra Amaducci DO and Gillian A. Beauchamp MD

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Nitrogen Dioxide Toxicity, Alexandra Amaducci DO and John W. Downs

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Duplication Cyst, Sachit Anand and Abdul Aleem MD

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Gastroesophageal Reflux Disease, Catiele Antunes, Abdul Aleem MD, and Sean A. Curtis

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Cystic Fibrosis And Liver Disease, Bindu Betapudi, Abdul Aleem MD, and Jiten P. Kothadoa

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Features, Evaluation, and Treatment of Coronavirus (COVID-19), Marco Cascella, Michael Rajnik, Abdul Aleem MD, Scott Dulebohn, and Raffaela Di Napoli

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Post Acute Coronavirus (COVID-19) Syndrome, Venu Chippa, Abdul Aleem MD, and Fatima Anjum

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Fascial Dehiscence, Matelin Crosen MD and Rovinder S. Sandhu MD

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Penetrating Groin Trauma, Matelin Crosen MD and Rovinder S. Sandhu MD

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Thoracoabdominal Injuries, Amy L. Dunn DO and Kimberly L. Fugok DO

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Chapter 114: Panceratic and Duodenal Injuries, Michael Steven Farrell MD, MS

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I-123 Uptake, Phillip D. Kim MD and Huyen D. Tran

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Posterior Tibial Tendon Dysfunction, Paul W. Knapp and Dustin Constant DPM

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Vitamin A, Emily McEldrew DO, Michael J. Lopez, and Harold Milstein

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Recurrent Ankle Sprain, Alexis T. Mugno and Dustin Constant

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Pediatric Palpitations Algorithm, Yalile Perez MD and B Cannon

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Lipodystrophies, Kelly Quinn DO, Shaylika Chauhan, and Stephen M. Purcell DO

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Sentinel Injuries, Teresa M. Romano MD and Susan K. Yaeger MD

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Gastrostomy Tube Replacement, Rushikesh Shah, Mili Shah, and Abdul Aleem MD

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Tendon Injuries, Robert Teixeira MD; Paul A. Sibley MD; and Robert X. Murphy JR, MD, MS

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Providing Access To Monoclonal Antibody Treatment Of Coronavirus (COVID-19) Patients In Rural And Underserved Areas, Davis Wood, Abdul Aleem MD, and David Davis

Podcasts

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ACMT Highlights Episode 34: Using ECLS and Mechanical Circulatory Support Devices to Support the Poisoned Patient, Gillian A. Beauchamp MD and Susanna Byram

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ACMT Highlights Episode 42: Neonatal Abstinence Syndrome - Opioids and Other Agents, Gillian A. Beauchamp MD and Lori Devlin

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ACMT Highlights Episode 36: The Truth About Expired Drugs - From Drug Shortages to Next Steps, Gillian A. Beauchamp MD and Brenna Farmer

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ACMT Highlights Episode 39: Retrograde Extrapolation and Other Ethanol Calculations, Gillian A. Beauchamp MD and Patrick Harding

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ACMT Highlights Episode 33: Renal Replacement Therapy - Adjusting Pharmaceutical Doses, Gillian A. Beauchamp MD and Joshua King

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ACMT Highlights Episode 41: Physical Dependence vs. Addiction vs. Substance Use Disorder, Gillian A. Beauchamp MD and Kurt Kleinschmidt

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ACMT Highlights Episode 37: Pharmacogenetic Variants that Impact Critical Care, Gillian A. Beauchamp MD and Andrew Monte

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ACMT Highlights Episode 40: Does Science Support the DRE Assessment, Gillian A. Beauchamp MD and Matthew Myers

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ACMT Highlights Episode 35: Advantage of the Bedside Medical Toxicologist, Gillian A. Beauchamp MD and Donna Segar

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ACMT Highlights Episode 43: Substance Use, Pregnancy and Stigma, Gillian A. Beauchamp MD and Mishka Terplan

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ACMT Highlights Episode 38: Brain Death Declaration in the Toxicology Patient, Gillian A. Beauchamp MD and Laura Tormoehlen

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What Your Period is Trying to Tell You, Julianna Grandinetti PA-C

A case reportof Multifactorial AMS: New Early-Onset Mild Cognitive Impairment in the Setting of Concurrent Major Depressive Disorder and COVID Positive Status with Prior Traumatic Brain Injury and Alcohol Use Disorder, Kara Jacobs MD

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Feeling Sick? Get Health Care From Your Couch, Lehigh Valley Health Network and Eric W. Bean DO

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What You Need to Know This Flu Season: A "Twindemic," Flu Shot Myths and More, Lehigh Valley Health Network and Terry Burger MBA, BSN, RN, NE-BC, CIC

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This Spring, Clean Up Your Health, Lehigh Valley Health Network and Kelly Strickler DO

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Be Summer Smart: Safety Tips for You and Your Kids, Lehigh Valley Health Network and Krystal Melich Trinkle RN

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Strong Is Sexy: Why Strength Training Looks Good on You, Lehigh Valley Health Network and Brielle Weida

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In “Vein” or Pain: How to Get Rid of Spider and Varicose Veins, Lehigh Valley Health Network and Eric Wilson MD

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Emergency Department Management of Pediatric Chest Pain at Lehigh Valley Health Network, Chetna Thawani, Andrew Bressler, Susan K. Yaeger MD, and Robert A. Palermo DO

Posters

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How Gender Impacts On-Shift Evidence-Based Medicine Activity and Patient Care, Jacob Albers; Ajay Varadhan; Jeffrey B. Brown; Estelle Cervantes BA; Kashyap Kaul DO; Shreyas Kudrimoti BA; Phillip Sgobba BS, MBS; William Spinosi DO; Joseph B. Zackary MD; Dawn M. Yenser; and Bryan G. Kane MD

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Analysis of Nursing Documentation After Pennsylvania Trauma Systems Foundation Significant Issue Report at Lehigh Valley Hospital- Muhlenberg, Lauren Allen; Joseph J. Stirparo MD; Kathleen E. Kane MD; Bree A. Harrison BSN, RN, TCRN; Emily Bear BSN, RN, CCRN, TCRN; Heather Butz; Amber Fetton RN; Ashley Dymond; and Melissa Teitsworth RN, BSN

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Risk Factors in Traumatic Injury with Periprosthetic Fracture, Michael Andres, Lauern Ladehoff, Victor Shen, Clara Freedman, Robert P Wessel MD, and Matthew D. Painter MD

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Gift of Life Regional Transplant Family Support Grant: The Impact on the Transplant Community at Lehigh Valley Health Network (LVHN), Tyler Baldes LSW, Talia Giordano, and Jan L. Weinstock

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Evaluation of Childhood Beverage Consumption: A Community Assessment for Program Development, Elaine Banerjee MD, MPH; Ashwini Kamath Mulki MD, MBBS, MPH; and Nicole M. Burgess

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Social Determinants Come to the Hospital: A QI-Initiative to Address Food Insecurity on an Inpatient Pediatric Unit, Kayle Barndt; Alicia Llewellyn; Anna V. Folk MSN, MSN, RN, CPN; and Claudia F. Busse MD