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Host CLIC4 expression in the tumor microenvironment is essential for breast cancer metastatic competence., Vanesa C Sanchez, Howard H Yang, Alayna Craig-Lucas MD, Wendy Dubois, Brandi L Carofino, Justin Lack, Jennifer E Dwyer, R Mark Simpson, Christophe Cataisson, Max P Lee, Ji Luo, Kent W Hunter, and Stuart H Yuspa

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A longitudinal study of naloxone opioid overdose awareness and reversal training for first-year medical students: specific elements require reinforcement., Reena K Sandhu, Michael V Heller, Jack Buckanavage, Benjamin Haslund-Gourley, Joshua Leckron, Brady Kupersmith, Nathaniel C Goss, Kyle Samson, and Annette B Gadegbeku

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Impact of colchicine on mortality and morbidity in COVID-19: a systematic review., Devang Sanghavi, Pankaj Bansal, Ikwinder Preet Kaur, Mohsin Sheraz Mughal, Chandana Keshavamurthy, Austin S Cusick DO, Jennifer Schram, Siva Naga S Yarrarapu, Abhishek R Giri, Nirmaljot Kaur, Pablo Moreno Franco, Andy Abril, and Fawad Aslam

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Early Onset Diffusion Abnormalities in Refractory Headache Disorders., Jonathan D Santoro, Peter K Moon, Michelle Han, Emily S McKenna, Elizabeth Tong, Sarah J MacEachern, Nils D Forkert, and Kristen W Yeom

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Severe delayed hypersensitivity reactions to IL-1 and IL-6 inhibitors link to common HLA-DRB1*15 alleles., Vivian E Saper, Michael J Ombrello, Adriana H Tremoulet, Gonzalo Montero-Martin, Sampath Prahalad, Scott Canna, Chisato Shimizu, Gail Deutsch, Serena Y Tan, Elaine F Remmers, Dimitri Monos, Timothy Hahn, Omkar K Phadke, Elaine Cassidy, Ian Ferguson, Vamsee Mallajosyula, Jianpeng Xu, Jaime S Rosa Duque, Gilbert T Chua, Debopam Ghosh, Ann Marie Szymanski, Danielle Rubin, Jane C Burns, Lu Tian, Marcelo A Fernandez-Vina, Elizabeth D Mellins, Jill A Hollenbach, and Catherine April Bingham MD

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NOONAN SYNDROME AND VENTRICULAR TACHYCARDIA - AN UNCHARTED TERRITORY, Bilal Saqi MD, Rahul Gupta MD, Makoto Nagahama MD, and Jeffrey Gordon

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PROVOCATIVE PROCAINAMIDE - UTILIZING PROCAINAMIDE IN GUIDING SUCCESSFUL EPICARDIAL CATHETER ABLATION IN A PATIENT WITH BRUGADA SYNDROME, Bilal Saqi MD, Makoto Nagahama MD, Rahul Gupta MD, and Jeffrey Gordon

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The effect of COVID-19 on the pressure injury reporting gap., Daniel C Sasson, Seema M Patel, Kaiti Duan, Corinne Signore, and Henry C Hsia

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Efficacy of Sex-Based Procedure Analysis in Widely Used Surgical Databases: Caution Is Advised., Daniel C Sasson, Sarah Phillips, Sumun Khetpal, Kaiti Duan, and Michael Alperovich

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Comparison of left atrial appendage parameters using computed tomography vs. transesophageal echocardiography for watchman device implantation: a systematic review & meta-analysis., Yasar Sattar, Ritika Kompella, Bachar Ahmad, Muhammad Aamir MD, Abdul-Rahman M Suleiman, Mohamed Zghouzi, Waqas Ullah, Fnu Zafrullah, Islam Y Elgendy, Sudharshan Balla, Akram Kawsara, and M Chadi Alraies

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Meta-Analysis Comparing Distal Radial Versus Traditional Radial Percutaneous Coronary Intervention or Angiography., Yasar Sattar, Usama Talib, Mohammed Faisaluddin, David Song, Hassan Mehmood Lak, Muhammad Aamir MD, Muhammad Zia Khan, Waqas Ullah, Islam Y Elgendy, Sudarshan Balla, Ramesh Daggubati, Akram Kawsara, Hani Jneid, Chadi M Alraies, and Mahboob Alam

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Is eNAMPT/visfatin a potential serum marker of papillary thyroid cancer?, Nadia Sawicka-Gutaj, Paulina Ziółkowska, Aleksandra Derwich, Paweł Gut, Agata Czarnywojtek, Michal Kloska, and Marek Ruchała

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Diagnosis of Intrauterine Pregnancy Despite the Presence of Etonogestrel Implant, Ryan J. Sawyers; Pratik M. Parikh DO; Jose Lazaro MD; and Marna R. Greenberg DO, MPH, FACEP

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Benefit of pulmonary subspecialty care for children with sickle cell disease and asthma., Shikha Saxena, Olufunke O. Afolabi-Brown MD, Lance Ballester, Nathaniel Schmucker, Kim Smith-Whitley, Julian Allen, and Anita Bhandari

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Gastric perforation from a migrating ventriculoperitoneal shunt: A case report and review of literature., Alessio Scarascia, Elias Atallah, Maria De Abreu Pineda, Robert Rosenwasser, and Kevin Judy

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A rare case of juvenile polyposis syndrome in a 19-month-old male presenting with intussusception and chronic anemia, Kyle Schank, Safwan Malas, and Marc Lessin MD

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Ocular examinations, findings, and toxicity in children taking vigabatrin., Yvette Schein, Keith D Miller, Ying Han, Yinxi Yu, Alejandra G de Alba Campomanes, Gil Binenbaum, and Julius T Oatts

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Emmetropization during Early Childhood., Yvette Schein, Yinxi Yu, Gui-Shuang Ying, and Gil Binenbaum

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Bruising on Arms in Older Patient, Stephen Schleicher MD

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DermDx: Asymptomatic Skin-Colored Patch on Scalp, Stephen Schleicher MD

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DermDx: Blister From Heating Pad, Stephen Schleicher MD

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DermDx: Bluish Nodule on Breast, Stephen Schleicher MD

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DermDx: Crusted, Bleeding Patch on Forehead, Stephen Schleicher MD

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DermDx: Firm Blue Lesion on Hand, Stephen Schleicher MD

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DermDx: Flesh-Colored Lesion Above Lip, Stephen Schleicher MD

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DermDx: Flesh-Colored Papule, Stephen Schleicher MD

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DermDx: Growth on Ear, Stephen Schleicher MD

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DermDx: Growth on Finger, Stephen Schleicher MD

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DermDx: Growth on Neck, Stephen Schleicher MD

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DermDx: Hair Loss After COVID-19, Stephen Schleicher MD

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DermDx: Patchy Rash on Chest, Stephen Schleicher MD

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DermDx: Pigskin-Like Rash on Neck, Stephen Schleicher MD

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DermDx: Red Bump on Nose, Stephen Schleicher MD

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DermDx: Red Papules on Foot After Skiing, Stephen Schleicher MD

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DermDx: Reticulated Rash on Inner Thigh, Stephen Schleicher MD

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DermDx: Solitary Hairless Lesion on Scalp, Stephen Schleicher MD

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DermDx: Suspicious Lesion on Back, Stephen Schleicher MD

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DermDx: White Scratch Marks on Leg, Stephen Schleicher MD and Amy DePalma

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DermDx: Dark Skin Patches, Stephen Schleicher MD, Nejib Doss, Safi Eldin E Ali, and Seemal R. Desai

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DermDx: Asymptomatic Rash on Neck and Trunk, Stephen Schleicher MD and Brittany Spinosa-Weber

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DermDx: Bump Under Nose, Stephen Schleicher MD and Alexandra Stroia

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DermDx: Deeply Pigmented Lesion on Upper Arm, Stephen Schleicher MD and Alexandra Stroia

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DermDx: Facial Growth in Older Man With Sun Damage, Stephen Schleicher MD and Alexandra Stroia

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DermDx: Itchy Rash on Back, Stephen Schleicher MD and Alexandra Stroia

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DermDx: Itchy Rash on Shoulders, Trunk, Stephen Schleicher MD and Alexandra Stroia

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DermDx: Nonitchy Facial Rash, Stephen Schleicher MD and Alexandra Stroia

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DermDx: Rash on Shin and Ophthalmopathy, Stephen Schleicher MD and Alexandra Stroia

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DermDx: Red Nodule on Abdomen, Stephen Schleicher MD and Alexandra Stroia

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Predictors of first-pass reperfusion for mechanical thrombectomy in acute ischemic stroke., Richard F Schmidt, Ahmad Sweid, Nikolaos Mouchtouris, Lohit Velagapudi, Nohra Chalouhi, M Reid Gooch, Robert H Rosenwasser, Pascal M Jabbour, and Stavropoula I Tjoumakaris

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Commentary on a Step Toward Environmental Sustainability in Mohs Surgery., Lauren Scott, Colby L. Presley, Carrie Diamond, and Christopher Stamey

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Suicide amongst transplant recipients: Trends and unique risk factors., Scott Serpico, Afshin Parsikia, Alireza Goodarzi MD, Rosy Manikath James, Naoru Koizumi, and Jorge Ortiz

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Neuromotor prosthetic to treat stroke-related paresis: N-of-1 trial., Mijail D Serruya, Alessandro Napoli, Nicholas Satterthwaite, Joe Kardine, Joseph McCoy, Namrata Grampurohit, Kiran Talekar, Devon M Middleton, Feroze Mohamed, Michael Kogan, Ashwini Sharan, Chengyuan Wu MD, and Robert H Rosenwasser

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Prevention of alcohol withdrawal syndrome in the surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document., Anupamaa Seshadri; Rachel Appelbaum; Samuel P Carmichael; Michael Steven Farrell MD, MS; Dina M Filiberto; Randeep Jawa; Lisa Kodadek; Samuel Mandell; M Victoria P Miles; Jasmeet Paul; Bryce Robinson; and Christopher P Michetti

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Ofatumumab for Post-Transplant Lymphoproliferative Disorder., Madhav Seshadri; Genevieve M Crane; and Usama Gergis MD, MBA

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Telestroke: Maintaining Quality Acute Stroke Care During the COVID-19 Pandemic., Theresa Sevilis, Mark McDonald, Amanda Avila, Gregory Heath, Lan Gao, Gayle O'Brien, Mohammed Zaman, Adam Heller, Muhammad Masud, Nima Mowzoon, and Thomas Devlin

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268: OCCUPATIONAL THERAPY OUTCOMES ON ADULTS MECHANICALLY VENTILATED SECONDARY TO COVID-19, Kyle Shaak BS and Lauren Reightler

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Community health workers providing asthma education., Samantha A. Shaak PhD, Kimberly C. Brown MD, Christine Reichart, and David Zimmerman MPH

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EP1224: TRANSPLANT EVALUATION PRACTICES FOR KIDNEY DONORS AND RECIPIENTS WITH HISTORY OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) AND NON-ALCOHOLIC STEATOHEPATITIS (NASH) IN THE UNITED STATES, Ashesh Shah MD

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Primary Non-Function Following Liver Transplant: Optimizing Retransplantation Strategies through Recipient Characterization, Ashesh Shah MD

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Abstract 13657: Evaluating Outcomes of Half-Dose Tissue Plasminogen Activator on Patients With Intermediate-Risk Pulmonary Embolism: A Single Center Study, Zaid M. Shahrori, Laith Alhuneafat, Sherin Sallam, Ahmad Jabri, Ahmad Al-Abdouh, Mohammed Mhanna, Adnan Yousaf MD, Yazan Abu Omar, Mohamed Farhan Nasser, and Aisha Siraj

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PROTEIN BEAM THERAPY CAUSING PERICARDITIS- A RARE CASE OF RADIATION INDUCED CARDIOTOXICITY, Swara Shah DO, Rahul Gupta MD, Muling Lin, Theresa Maitz DO, Gary Freedman, Deborah W Sundlof DO, and Cheri Silverstein Fadlon MD

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STONES, BONES, GROANS AND ECG UNDERTONES: HYPERCALCEMIA INDUCED RARE ELECTROCARDIOGRAPHIC CHANGES, Swara Shah DO, Rahul Gupta MD, and Benjamin Sanchez MD

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One-Year Outcome Trajectories and Factors Associated with Functional Recovery Among Survivors of Intracerebral and Intraventricular Hemorrhage With Initial Severe Disability., Vishank A Shah, Richard E Thompson, Gayane Yenokyan, Julian N Acosta, Radhika Avadhani, Rachel Dlugash, Nichol McBee, Yunke Li, Bjorn M Hansen, Natalie Ullman, Guido Falcone, Issam A Awad, Daniel F Hanley, and Wendy C Ziai

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S3630 Metastatic Breast Carcinoma Presenting as Gastric Outlet Obstruction, Aamir Shahzad MD

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Impact of COVID-19 in hematopoietic stem cell transplant recipients: A systematic review and meta-analysis., Moazzam Shahzad, Sibgha Gull Chaudhary, Muhammad Usman Zafar, Maha A Hassan, Ali Hussain, Fatima Ali, Iqra Anwar, Mamoon Ahmed, Nausheen Ahmed, Sharad Khurana, Muhammad A Rauf, Faiz Anwar, Peiman Hematti, Natalie S Callander, Sunil H Abhyankar, Joseph P McGuirk, and Muhammad Umair Mushtaq

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High incidence of large bore temporary hemodialysis catheter malfunction in patients with COVID-19 related kidney injury., Srinidhi Shanmugasundaram, Aleksander Kubiak, Aleena Dar, Abhishek Shrinet, Nirav Chauhan, Humza Haque, Abhishek Kumar, and Pratik A Shukla

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An Internally Validated Prognostic Risk-Score Model for Disease-Specific Survival in Clinical Stage I and II Merkel Cell Carcinoma., Adrienne B Shannon, Richard J Straker, Michael J Carr, James Sun, Karenia Landa, Kirsten Baecher, Kevin Lynch, Harrison G Bartels, Robyn Panchaud, Luke J Keele, Michael C Lowe, Craig L Slingluff, Mark J Jameson, Kenneth Y Tsai, Mark B Faries, Georgia M Beasley, Vernon K Sondak, Giorgos C Karakousis, Jonathan S Zager, and John T Miura

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ASO Visual Abstract: An Internally Validated Prognostic Risk Score Model for Disease-Specific Survival in Clinical Stage I and II Merkel Cell Carcinoma., Adrienne B Shannon, Richard J Straker, Michael J Carr, James Sun, Karenia Landa, Kirsten Baecher, Kevin Lynch, Harrison G Bartels, Robyn Panchaud, Luke J Keele, Michael C Lowe, Craig L Slingluff, Mark J Jameson, Kenneth Y Tsai, Mark B Faries, Georgia M Beasley, Vernon K Sondak, Giorgos C Karakousis, Jonathan S Zager, and John T Miura

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Predictive Effect of Bone Conduction Pattern on Hearing Outcomes of Stapes Surgery., Scott B Shapiro, Meghan Grojean, Michael Hong, Noga Lipschitz, Joseph T Breen, Myles L Pensak, and Ravi N. Samy MD

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Cochlear Fibrosis after Vestibular Schwannoma Resection via the Middle Cranial Fossa Approach., Scott Shapiro, Nathan Kemper, Austin Jameson, Noga Lipschitz, Michael Hazenfield, Mario Zuccarello, and Ravi N. Samy MD

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The role of serial right heart catheterization in risk stratification and management of pulmonary arterial hypertension., Dikshya Sharma, Ravi J Shah, Jayakumar Sreenivasan, Paritosh Kafle, Rahul Gupta MD, Avi Levine, Gregg M Lanier, and Wilbert S Aronow

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Burden of early hospitalization after simultaneous liver-kidney transplantation: Results from the US Multicenter SLKT Consortium., Pratima Sharma, Jiaheng Xie, Leyi Wang, Min Zhang, John Magee, Adeline Answine, Pranab Barman, Jennifer Jo, Jasmine Sinha, Aaron Schluger, Gabriel J Perreault, Kara E Walters, Giuseppe Cullaro, Randi J Wong, Natalia Filipek, Scott W Biggins, Jennifer C Lai, Lisa B VanWagner, Elizabeth C Verna, and Yuval A Patel

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NTR 2.0: a rationally engineered prodrug-converting enzyme with substantially enhanced efficacy for targeted cell ablation., Abigail V Sharrock, Timothy S Mulligan, Kelsi R Hall, Elsie M Williams, David T White, Liyun Zhang, Kevin Emmerich, Frazer Matthews, Saumya Nimmagadda, Selena Washington, Katherine D Le, Danielle Meir-Levi DO, Olivia L Cox, Meera T Saxena, Anne L Calof, Martha E Lopez-Burks, Arthur D Lander, Ding Ding, Hongkai Ji, David F Ackerley, and Jeff S Mumm

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HaNDL: A Migrainous Headache That Should Not Be Mis-Handled, Sathvik Shastry MD, Cleo Z. Reyes MD, Erafat Rehim MD, and Kathryn Cheponis MD

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The Relationship Between Opioid Use and Healthcare Utilization in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis., Jessica L Sheehan, Janson Jacob MD, Elliot M Berinstein, LaVana Greene-Higgs, Calen A Steiner, Sameer K Berry, Carol Shannon, Shirley A Cohen-Mekelburg, Peter D R Higgins, and Jeffrey A Berinstein

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Porokeratoma: A distinct variant of porokeratosis., Alexander K Sherban; Collin G Fuller; Thomas Griffin; and Jason B. Lee, MD

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A Prospective Study of Intraocular Pressure Spike and Failure After Gonioscopy-Assisted Transluminal Trabeculotomy in Juvenile Open-Angle Glaucoma: A Prospective Study of GATT in JOAG., Yan Shi, Huaizhou Wang, Julius T Oatts, Chen Xin, Peng Yin, Li Zhang, Jiaxin Tian, Yinghan Zhang, Kai Cao, Ying Han, and Ningli Wang

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Learning curves in robotic neurosurgery: a systematic review., Nathan A Shlobin, Jonathan Huang, and Chengyuan Wu MD

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The Anemia Stress Index-Anemia, Transfusions, and Mortality in Patients with Continuous Flow Ventricular Assist Devices., Supriya Shore, Thomas C Hanff, Jeremy A Mazurek, Arieh Fox, Monique S Tanna, Edward W Grandin, Robert Zhang, Joyce Wald, Carli Peters, Michael A Acker, Pavan Atluri MD, J Eduardo Rame, Lee R Goldberg, Mariell Jessup, Kenneth B Margulies, and Edo Y Birati

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Breast abscess in two Nepalese newborns: An unusual series., Ashish Lal Shrestha MD and Aakash Mishra

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Abstract 9444: Differences in Hospital Outcomes Following Watchman's Procedure Based on CHA2DS2VASc Score: Insight From National Inpatient Sample Database, 2016-2019, Biraj Shrestha MD

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RACIAL DISPARITIES IN OUTCOMES OF ACUTE PULMONARY EMBOLISM, Biraj Shrestha MD

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Impact of Pre-Existing Right Bundle Branch Block on In-Hospital Outcomes Following Transcatheter Aortic Valve Replacement: Insight from National Inpatient Sample Database, 2016-2019., Biraj Shrestha MD, Rebecca DeBoer DO, Bidhya Poudel, Pratik Gyawali, and Anthony Donato

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Pericardial Mesothelioma Presenting as Constrictive Pericarditis., Biraj Shrestha MD, Rishin Handa, Bidhya Poudel, and Rittu Hingorani

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Trends and Outcomes of ST-Segment-Elevation MI in Hospitalized Patients Without Standard Modifiable Cardiovascular Risk Factors., Biraj Shrestha MD, Agnieszka Mochon, Bidhya Poudel, Dilli Poudel, and Anthony Donato

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Lambl's Excrescences Associated with Cardioembolic Stroke., Biraj Shrestha MD, Arpan Pokhrel, Ibiyemi Oke, Anish Paudel, Bidhya Timlisina, Prem Parajuli, Sijan Basnet, and Bidhya Poudel

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A Challenging Case of Mechanical Mitral Valve Obstruction., Biraj Shrestha MD, Bidhya Poudel, and Tuoyo Mene-Afejuku

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National Yearly Trend of Utilization and Procedural Complication of the Watchman Device in the United States., Biraj Shrestha MD, Bidhya Poudel, DilliRam Poudel, and Julian Diaz Fraga

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Pseudohyperkalemia Associated With Leukemia., Biraj Shrestha MD, Swarup Sharma Rijal, Arpan Pokhrel, Anish Paudel, Krantikiran Baral, Bidhya Poudel, Sijan Basnet, and Anthony Donato

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Imaging of Immune Checkpoint Inhibitor Immunotherapy for Non-Small Cell Lung Cancer., Girish S Shroff, Chad D Strange, Jitesh Ahuja, Mehmet Altan, Ajay Sheshadri, Ebru Unlu, Mylene T Truong, and Ioannis Vlahos

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Differential fuel utilization in liver transplant recipients and its relationship with non-alcoholic fatty liver disease., Mohammad S Siddiqui, Samarth S Patel MD, Mikael Forsgren, Anh T Bui, Steve Shen, Taseen Syed, Sherry Boyett, Shanshan Chen, Arun J Sanyal, Susan Wolver, Danielle Kirkman, Francesco S Celi, and Chandra S Bhati

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In-vivo platelet activation and aggregation during and after acute atherothrombotic myocardial infarction in patients with and without Type-2 diabetes mellitus treated with ticagrelor., Narayana Sarma V Singam, Bahjat AlAdili, Alok R Amraotkar, Amanda R Coulter, Ayesha Singh, Siddhesh Kulkarni, Riten Mitra, Omar Noori Daham, Allison E Smith, and Andrew P DeFilippis

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Calculation of Mitral Valve Area by Continuity Equation Using Velocity-Time Integral From Mitral Valve Orifices After Mitral Clip., Narayana Sarma V Singam, Diana Otero, Bahjat Al Adili, Kendra J Grubb, Michael P Flaherty, Dana M Settles, and Marcus F Stoddard

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Cardiovascular Mechanisms of Exercise Intolerance in Older Patients with Heart Failure., Narayana Sarma V Singam, Meir Tabi, and Jerome L Fleg

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NON-HISPANIC BLACK AND AFRICAN AMERICAN (NHB/AA) PATIENTS: UNDERREPORTED AND UNDERREPRESENTED IN RANDOMIZED CONTROLLED TRIALS OF LIPID LOWERING THERAPY, Harjit Singh

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Learning Deficits and Attenuated Adaptive Stress Response After Early-Life Seizures in Zebrafish., Harsimran Singh, Alfonsina Ramon, Dana Finore, Kaleigh Burnham DO, Scott McRobert, and Jocelyn Lippman-Bell

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Microfluidic Approaches and Methods Enabling Extracellular Vesicle Isolation for Cancer Diagnostics., Premanshu Kumar Singh, Aarti Patel, Anastasia Kaffenes, Catherine Hord, Delaney Kesterson, and Shaurya Prakash

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ODP076 A Unique Case of Iatrogenic Hypermagnesemia Induced Symptomatic Hypocalcemia, Andrew Singles DO, Vijaykumar Sekar MD, Mohammad Uzair Abdul Rauf, and Shamsuddin Shaik MD

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Immunoscore Is Prognostic in Low-Risk and High-Risk Stage III Colon Carcinomas Treated With Adjuvant Infusional Fluorouracil, Leucovorin, and Oxaliplatin in a Phase III Trial., Frank A Sinicrope, Qian Shi, Aurelie Catteau, Graham M Poage, Tyler J Zemla, Bernhard Mlecnik, Al B Benson, Sharlene Gill, Richard M Goldberg, Morton S Kahlenberg, Suresh G. Nair MD, Anthony F Shields, Thomas C Smyrk, Jerome Galon, and Steven R Alberts

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Anatomic patterns of recurrence in biliary tract cancers: does primary tumor site matter?, Andrew J Sinnamon, Anthony C Wood, Megan A Satyadi, Catherine V Levitt, Olivia A. Hardy, Mintallah Haider, Richard D Kim, Daniel A Anaya, and Jason W Denbo